A novel conserved domain of SAYP coactivator mediates the interaction of TFIID and brahma transcription complexes

Autor:	N. V. Soshnikova, N. E. Vorob’eva, Yu. L. Kuz’mina, Yu. V. Nikolenko, Elena N. Nabirochkina, Sofia G. Georgieva, Yu. V. Shidlovskii
Rok vydání:	2010
Předmět:	Genetics genetic processes fungi Protein domain information science Biophysics macromolecular substances Biology Chromatin remodeling TAF1 Structural Biology Transcription (biology) TAF4 TAF2 Coactivator health occupations Transcription factor II D
Zdroj:	Molecular Biology. 44:769-775
ISSN:	1608-3245 0026-8933
DOI:	10.1134/s0026893310050134
Popis:	Using the S2 cell system of Drosophila melanogaster, it was shown that the key protein domain mediating the interaction of TFIID and Brahma transcriptional complexes within the BTFly supercomplex is the evolutionary conserved SAY domain of SAYP. TFIID and Brahma coactivators participated in the reporter gene activation induced by the SAY domain in cellular nuclei. The components of TFIID and Brahma directly interacting with SAY were identified.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::059aae83b5628b21f63b81b85a79615c https://doi.org/10.1134/s0026893310050134 Zobrazit plný text záznamu Full text from SpringerLink