Transcription activation by the resistance protein AlbA as a tool to evaluate derivatives of the antibiotic albicidin
| Autor: | Simone Kosol, Lida Rostock, Jonas Barsig, Theresa Tabarelli, Kay Hommernick, Marcel Kulike, Tobias Eulberg, Maria Seidel, Iraj Behroz, Leonardo Kleebauer, Stefan Grätz, Andi Mainz, Roderich D. Süssmuth |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Chemical Science. 14:5069-5078 |
| ISSN: | 2041-6539 2041-6520 |
| DOI: | 10.1039/d3sc00955f |
| Popis: | Exploiting the transcription regulatory activity of the AlbA resistance protein enables the design of improved albicidin analogs that can overcome the resistance mechanism. |
| Databáze: | OpenAIRE |
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