| Popis: |
Background: Acute retinal necrosis is considered as a rare infectious uveitis. This condition is usually caused by Varicella-zoster virus or Herpes simplex virus. At the time being, acute retinal necrosis caused by co-infection of multiple viruses is sorely rare report. Herein, we report an immunocompetent patient who developed ARN with co-infection of Herpes Simplex Virus (type I and II) and Varicella-Zoster Virus (VZV).Findings: An adult immunocompetent man presented with complain of decreased vision of the right eye from 12 days before. Examination of the right eye revealed severe conjunctival injection, fine diffuse keratic precipitates, 3+ anterior chamber and vitreous cells, slightly elevated intraocular pressure (26), blurred optic disk with hemorrhagic patches, and occlusive vasculitis plus confluent necrotizing patches on the peripheral retina compatible with diagnosis of acute retinal necrosis. The patient has been admitted and underwent for sampling from intra-ocular fluids which showed presence of HSV I & II and VZV on real-Time PCR of vitreous specimens confirmed by rechecking. We used of intravenous acyclovir followed by oral acyclovir and oral prednisolone to control the disease which was successful. Conclusions: Although rare, we speculate multi viral infection may be considered in the physiopathology of acute retinal necrosis. |
