Holmium Laser Enucleation of Prostate Within 6 Weeks of Transrectal Ultrasound Guided Prostate Biopsy is Safe and Effective
| Autor: | Nicholas Smith, Hemendra N. Shah, Mohamed Etafy, Rashmi H. Shah, Indraneel Banerjee, Jonathan Katz, Mia R. Gonzalgo, Emmanuel Alejandro Garcia Lopez |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Prostate biopsy medicine.diagnostic_test business.industry Urology Enucleation Ultrasound 030232 urology & nephrology Perioperative medicine.disease Ultrasound-Guided Prostate Biopsy Surgery 03 medical and health sciences Bladder outlet obstruction Prostate cancer 0302 clinical medicine medicine.anatomical_structure Prostate 030220 oncology & carcinogenesis medicine business |
| Zdroj: | Urology. 148:88-92 |
| ISSN: | 0090-4295 |
| DOI: | 10.1016/j.urology.2020.11.021 |
| Popis: | Objective To evaluate the safety and efficacy of performing Holmium laser enucleation of the prostate (HoLEP) for the treatment of bladder outlet obstruction secondary to an enlarged prostate within 6-weeks of a transrectal ultrasound (TRUS) guided prostate biopsy. Materials and Methods We performed a retrospective review of patients who underwent a HoLEP at our institution, excluding any patients with a confounding urologic history and compared patients who underwent a TRUS-guided 6- or 12-core prostate biopsy, and then underwent a HoLEP within 6 weeks (study group) with all other patients (control group). Our primary outcomes were enucleation efficiency (EE) and perioperative complication rate. Our secondary outcomes included postoperative drop in hemoglobin, duration of catheterization, length of hospital stay, voiding metrics at 1 and 6 months and rate of incidental prostate cancer diagnosed on histopathological examination of prostate specimens after HoLEP. To test for differences between the study and control groups, we performed independent sample t-test (2-tailed) and chi-square tests for quantitative and qualitative variables, respectively. P values of Results 552 patients met inclusion criteria and 84 patients underwent prostate biopsy within a period of 45 days prior to HoLEP. Enucleation efficiency was higher in the study group (P = 0.00). There was no significant difference between the 2 groups regarding perioperative complications, postoperative voiding outcomes, or rate of incidental prostate cancer detection. Conclusions TRUS prostate biopsy performed within 6 weeks of HoLEP does not negatively impact operative difficulty or treatment outcome. |
| Databáze: | OpenAIRE |
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