Clonidine versus Tramadol for postanesthetic shivering: a randomized clinical trial study
| Autor: | Mahmood Reza Mohaghegh, Mehrdad Mesbah Kiaee, Seyedeh Fatemeh Morsali, Gholamreza Movasseghi, Mona Morsali, Ali Morsali, Masood Ghorbanloo |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry Postanesthetic shivering Repeated measures design medicine.disease General Biochemistry Genetics and Molecular Biology Surgery Clonidine law.invention Clinical trial Blood pressure Randomized controlled trial law Anesthesia Shivering medicine Tramadol medicine.symptom business medicine.drug |
| Zdroj: | Biomedical Research and Therapy. 4:1716 |
| ISSN: | 2198-4093 |
| Popis: | Introduction: To compare the effects of oral clonidine and tramadol on shivering caused by spinal anesthesia in patients undergoing transurethral lithotripsy (TUL). Methods: The present study is a triple-blind clinical trial conducted on 80 elective urologic surgical candidates during 2016-2017 at Tehran Hasheminejad Hospital in Iran. Using the Balanced Block Randomization method, the patients were randomly assigned into two groups (40 patients per group) 90 minutes before performing spinal anesthesia. The first group (group C) received 150 µg of oral clonidine and the second group (group T) received 50 mg of oral tramadol. Body temperature, core body temperature, heart rate, diastolic blood pressure and shivering were recorded for the patients at different time periods, and entered in the SPSS22 software program. The above variables were then statistically analyzed using independent sample T-tests chi-squared tests and Repeated Measure ANOVA. Results: The results of this study indicated that there was a significant statistical difference (P0.05). Conclusion: Clonidine and tramadol treatment groups were only significantly different in terms of body temperature and core temperature. Therefore, it is recommended that other precise randomized clinical trials be performed to ensure the accuracy of the results of this study. Peer Review Details Peer review method: Single-Blind (Peer-reviewers: 02) Peer-review policy Plagiarism software screening?: Yes Date of Original Submission: 04 September 2017 Date accepted: 30 September 2017 Peer reviewers approved by: Dr. Lili Hami Editor who approved publication: Dr. Phuc Van Pham |
| Databáze: | OpenAIRE |
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