| Autor: |
Tommaso Simoncini, Guja Bernacchi, Silvia Pisaneschi, Paolo Mannella, Stefania Spina, Andrea R. Genazzani, Elena Cecchi, Silvia Di Bello |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
ISGE Series ISBN: 9783319034935 |
| DOI: |
10.1007/978-3-319-03494-2_25 |
| Popis: |
The climacteric syndrome is a complex condition characterized by a set of symptoms and degenerative changes that ensue due to the decline in production of sex steroids by the ovaries. This set of changes identifies women at additional risk of degenerative changes during ageing and calls for personalized interventions. Hence, there is a need for safe methods for the short- and long-term management of postmenopausal women. Hormone replacement therapy (HRT) is widely used for the relief of menopausal symptoms and for the prevention of diseases linked to long-term hormonal deprivation. The use of HRT has increased rapidly in the past decade but is currently a subject of debate because of the possible negative effects on the breast. Other molecules have been studied as alternatives to standard hormonal replacement therapy to relief the symptoms also in women with contraindications to hormones or who refuse sex steroids for personal reasons. The aim of this chapter is to discuss the results of the principal studies performed in these last few years on the safety of HRT and of other climacteric therapies and to suggest how to personalize therapies in climacteric women. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
