Better Health Related Quality of Life Reduced Elevated Lp(a) Levels in Man

Autor: Jinlan Bao, ZhuZhi Wen, Ying Tang, Runlu Sun, Canxia Huang, JingFeng Wang, Yuling Zhang
Rok vydání: 2020
DOI: 10.21203/rs.3.rs-67835/v1
Popis: Background: Elevated Lipoprotein(a) (Lp(a)) is an independent risk factor for premature coronary heart disease (PCHD), but drug therapy rarely changes. Recently, health related quality of life (HRQOL) has been used to measure the prognosis of PCHD, but it is unclear whether HRQOL can improve Lp(a) levels. Aim: To explore whether HRQOL score in PCHD patients is closely related to increased Lp(a) level.Methods: The retrospective study included 448 male patients, 218 male patients with PCHD (49.63±3.72 years) and 230 male healthy controls, the two groups were matched in age. According to Lp(a) levels, they were divided into normal Lp(a) group (Lp(a)Results: Elevated Lp(a) subgroup had more PCHD patients 150(65.5%) than normal Lp(a) subgroup 68(31.1%), PConclusion: Better HRQOL may be an important indicator to reduce the risk of high Lp(a) and PCHD in man.
Databáze: OpenAIRE