Application of the Novel Tandem Process Diels-Alder Reaction/Ireland-Claisen Rearrangement to the Synthesis of rac-Juvabione and rac-Epijuvabione

Autor:	Helen Stoeckli-Evans, Joerg Velker, Olivier Vallat, Reinhard Neier, Nicolas Soldermann
Rok vydání:	2000
Předmět:	Tandem fungi Organic Chemistry Biochemistry Catalysis Inorganic Chemistry chemistry.chemical_compound chemistry Scientific method Drug Discovery Organic chemistry Physical and Theoretical Chemistry Juvabione Ireland–Claisen rearrangement Diels–Alder reaction
Zdroj:	Helvetica Chimica Acta. 83:2266-2276
ISSN:	0018-019X
DOI:	10.1002/1522-2675(20000906)83:9<2266::aid-hlca2266>3.0.co;2-t
Popis:	The novel tandem process Diels-Alder reaction/Ireland-Claisen rearrangement shows a high diastereoselectivity for the Ireland-Claisen rearrangement starting from the endo-product of the Diels-Alder reaction. Based on this mechanistic knowledge, the novel tandem process could be applied to the synthesis of rac-juvabione.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::052a708c2a6f47d8cd0dfdee5428bd6f https://doi.org/10.1002/1522-2675(20000906)83:9<2266::aid-hlca2266>3.0.co Zobrazit plný text záznamu Plný text