| Popis: |
Like arrhenoblastomas, the adrenal-like ovarian tumors tend to masculinize their hosts but the tendency toward the production of a bizarre type of fat distribution, the occurrence of purplish striae, arterial hypertension, polycythemia and so forth, relate them more closely to adrenal cortical carcinomas from a functioning standpoint. Histologically, the tumors do not appear to arise through luteinization of pre-existing granulosa-cell neoplasms and an origin from adrenal cortical rests seems more logical than does a derivation from corpora lutea. An origin by way of teratomatous development likewise remains unproved. Some of the tumors appear to be cytologically malignant and in one instance death resulted from metastasis. |
