Autor: |
Peter Kiefer, Gerhard Lingg, Peter Christian Endler |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
International Journal of High Dilution Research - ISSN 1982-6206. 11:03-18 |
ISSN: |
1982-6206 |
DOI: |
10.51910/ijhdr.v11i38.526 |
Popis: |
Our previous paper described methodological problems and a generally acceptable pooling method for metamorphosis experiments and application of that method to the results of multicentre experiments performed over the course of two decades (1990 - 2010) on highland amphibians (Rana temporaria) treated with a homeopathically prepared high dilution of thyroxine (“30xâ€ÂÂ). Differences between treatment groups thus calculated were in line with those obtained with other pooling methods: Thyroxine 30x does slow down metamorphosis in highland amphibians. This follow up paper provides a broader background on metamorphosis physiology and describes application of the pooling method to experiments with Rana temporaria from lowland biotopes both with a moderate dilution of thyroxine (“8xâ€ÂÂ) and with 30x. Analogously prepared water was used for control (water 8x or 30x). Development was, again as above, monitored by documenting the number of animals that had entered the 4-legged stage. Experiments were carried out between 1990 and 2000 by different researchers independently and in blind. As it is well known, metamorphosis can be speeded up by thyroxine 10-8 mol/l; interestingly, thyroxine 8x may produce a reverse, i.e. inhibiting effect (p < 0.01). In contrast to the inhibiting effect of thyroxine 30x on highland larvae (see above), 2-legged lowland larvae did not react to thyroxine 30x (p > 0.05). However, an inhibiting effect on lowland larvae was found when animals were treated from the spawn stage on (p < 0.01). |
Databáze: |
OpenAIRE |
Externí odkaz: |
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