ChemInform Abstract: Reactions of o-Bromoacetylacylphenones with Several Primary Amines

Autor: Hirofumi Ishida, Kiyoshi Kanie, Seiko Nan'ya, Noriyuki Ito, Yasuo Butsugan
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 26
ISSN: 0931-7597
DOI: 10.1002/chin.199551054
Popis: o-Monobromoacetylacylphenones, 3a and 3b reacted with hydroxylamine or hydrazine hydrate to produce heterocycles, 2,3-benzoxazine or phthalazine derivatives. The reaction of bromoacetyl group of 3a and 3b with several thioamides afforded thiazole derivatives in high yields. Whereas o-dibromoacetyl-benzophenoe 2a reacted with aniline or cyclohexylamine to produce non-heterocycles, 2-substituted-iminophenylindanones and the mechanism for the formation of these non-heterocycles is proposed.
Databáze: OpenAIRE