| Popis: |
This study was performed to investigate the effects of puffed-red ginseng (PRG) powder and drink on blood glucose level and serum lipid profile in streptozotocin (STZ)-induced diabetic rats. For the experimental design, STZ-induced diabetic rats were fed PRG powder-supplemented diets (0.3%, 0.6%) and diluted drinks (0.14%, 0.28%) for 6 weeks. Concentrations of blood glucose during the experimental period decreased to 18.3 mg/dL in the 0.6% PRG diet group and 15.1 mg/dL in the 0.14% PRG drink group. Average reduction rate of blood glucose in the last week compared to reference blood glucose concentration decreased by 19.2% (A group), 37.4% (B group), 18.7% (C group), and 17.3% (D group) in the PRG treatment groups, respectively. These results indicate that PRG affects blood glucose via ginseng saponins administered in diet or drinking water, thereby suggesting that PRG has the ability to prevent increasing blood glucose in mild-induced diabetic rats. Key words: puffed-red ginseng, blood glucose, STZ-induced diabetic rats, ginsenoside, serum lipid profileReceived 11 June 2015; Accepted 30 June 2015 Corresponding author: Chan-Kyu Han, Korea Food Research Insti-tute, Seongnam, Gyeonggi-do 13539, Korea E-mail: ckhan@kfri.re.kr, Phone: +82-31-780-9236 |
