Effects of non-surgical periodontal therapy on the glomerular filtration rate of the kidney: an exploratory trial
| Autor: | Michele Vano, Silvia Cei, Mario Gabriele, Maurizio S. Tonetti, Fabio La Ferla, Filippo Graziani |
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| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Creatinine Kidney biology business.industry C-reactive protein Renal function urologic and male genital diseases Fibrinogen Gastroenterology chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Cystatin C Internal medicine biology.protein Periodontics Medicine Serum amyloid A business Blood urea nitrogen medicine.drug |
| Zdroj: | Journal of Clinical Periodontology. 37:638-643 |
| ISSN: | 1600-051X 0303-6979 |
| DOI: | 10.1111/j.1600-051x.2010.01578.x |
| Popis: | Graziani F, Cei S, La Ferla F, Vano M, Gabriele M, Tonetti M. Effects of non-surgical periodontal therapy on glomerular filtration rate of the kidney: an exploratory trial. J Clin Periodontol 2010; 37: 638–643. doi: 10.1111/j.1600-051X.2010.01578.x. Abstract Objective: To determine whether non-surgical periodontal treatment (PT) would exert, in subjects with generalized chronic periodontitis (GCP), some beneficial effect on renal function as indicated by surrogate measures of the glomerular filtration rate (GFR). Material and Methods: Twenty GCP systemically healthy subjects were treated with PT. Serum samples were collected at baseline and 1 day, 7, 30, 90 and 180 days after treatment. GFR was evaluated using cystatin C, a serum marker and modification of diet in renal disease (MDRD), an equation involving creatinine, urea and albumin. Serum markers of systemic inflammation such as C-reactive protein (CRP), D-dimer, serum amyloid A (SAA) and fibrinogen were also assessed. Results: The cystatin C level decreased significantly from baseline to the end of the trial (p |
| Databáze: | OpenAIRE |
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