Hydrochloric Acid and Total Chlorine Content of Pure Gastric Juice Produced After Histamine Injection

Autor: K. K. Sherwood, Hilding Berglund, Harold Wahlquist
Rok vydání: 1927
Předmět:
Zdroj: Experimental Biology and Medicine. 24:927-929
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-24-3641
Popis: The acid curve obtained from a fractional analysis of an ordinary test meal is at present in a stage of reinterpretation. This new interpretation is based on Boldyreff's theory about the automatic regulation of the acidity in the stomach.1 Clinically this theory is being supported chiefly by work from Guy's Hospital (Bolton and Goodhart;2 Baird, Campbell and Hern;3 Ryle4). The chief point in the interpretation is that the total chlorides of the gastric content represent a true expression of the acid production in the stomach. The difference between the curve expressing the free hydrochloric acid and the total chloride curve, therefore, according to this theory represents the extent of neutralization of acid either by combining with protein or by neutralization with regurgitated alkaline duodenal content, particularly pancreatic juice. The value of this theory evidently depends upon several factors. One important point to be ascertained is whether in the pure gastric juice chlorides are present in other fo...
Databáze: OpenAIRE