Prognostic significance of longitudinal evaluation on egfr mutant ctdna during tki treatment in nsclc

Autor: F.V. Moiseenko, V.V. Klimenko, V.V. Egorenkov, A. S. Zhabina, N.A. . Rjsev, M.L. . Stepanova, A. Myslik, N. H. Abduloeva, Nikita M. Volkov, E. V. Artemieva, Vladimir M. Moiseyenko
Rok vydání: 2020
Předmět:
Zdroj: Practical oncology. 21:296-304
ISSN: 1726-9814
Popis: Detection of EGFR mutations in tumor tissue is the gold standard for prescribing tyrosine kinase inhibitor therapy.However even in the same molecularly defined population effect of the treatment, response duration and survival might differ significantly. We did a prospective clinical trial to assess ctDNA-based EGFR mutations as a prognostic marker for patients with lung adenocarcinoma receiving TKI as first-line treatment.
Databáze: OpenAIRE