Some results are striking - what about lung function in adults with congenital heart disease?
| Autor: | J Hock, M Bessar, R Dalla Pozza, P Ewert, A Hager |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | European Journal of Preventive Cardiology. 30 |
| ISSN: | 2047-4881 2047-4873 |
| Popis: | Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Stiftung KinderHerz Weserstr. 101 45136 Essen. Background During the last years, lung function tests became of high interest in patients with a congenital heart defect (CHD). However, data are still rare and mostly concentrate on spirometry, investigating forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and its ratio (FEV1/FVC). Purpose This study prospectively examined patients with CHD regarding their lung function. Data reported were FVC, FEV1, and FEV1/FVC (spirometry) as well as total lung capacity (TLC) and residual volume, presented as its ratio to TLC (RV/TLC) and compared to the latest Global Lung Initiative reference values (2021). Methods From April 2018 to October 2022, one hundred eighty-six adults with CHD (32 ± 10 years, 83 female) participated in the study. Their results (z-scores) were compared with the student’s T-test against zero. Results Patients mostly reached normal values but differed significantly in FVC-z (-1.1 ± 1.2, p-1.645 as normal results, 33% had striking results: 43 showed a reduced FVC (FVC-z-1,645), which stands for a non-specific pattern, and 26 patients (60%) had a real restriction, which was only detected via body plethysmography. Conclusions Patients with CHD and a reduced FVC in spirometry need to undergo body plethysmography. Most of them have unrevealed ventilatory restrictions that should be further analyzed and treated if needed. |
| Databáze: | OpenAIRE |
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