Positive Histological Tuberculous Findings Despite Stable Sterility of the Urine on Culture

Autor:	K. Haubensak, H.R. Osterhage, V. Fischer
Rok vydání:	1980
Předmět:	Chemotherapy medicine.medical_specialty Tuberculosis business.industry Sterility Urology medicine.medical_treatment Isoniazid Urine medicine.disease Nephrectomy Surgery medicine business Rifampicin Ethambutol medicine.drug
Zdroj:	European Urology. 6:116-118
ISSN:	1873-7560 0302-2838
DOI:	10.1159/000473303
Popis:	The therapy of genitourinary tuberculosis has changed: 'nephrectomie necessaire' has been replaced by 'nephrectomie opportune'. Today, it is generally assumed that tuberculosis can be cured completely by chemotherapy. The following question must, however, be asked: How far may the stable sterility of the urine be considered as a complete cure? In order to assess the efficiency of chemotherapy as a function of time and dosage, the activity of tuberculosis of the kidneys was investigated on the basis of the histological preparation, after removal of the tuberculous renal tissue. Despite stable sterilization of the urine, 15% of the cases showed active tuberculosis. Using the triple therapy combination of rifampicin, ethambutol and isoniazid, the disease was found no longer to be active after 2--3 months of treatment in 90% of the cases. A longer period of treatment brought no further improvement.
Databáze:	OpenAIRE
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