| Autor: |
Rina Toyoda, Shigeo Iijima, Naoki Uga |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Journal of Neonatal-Perinatal Medicine. 3:241-244 |
| ISSN: |
1934-5798 |
| DOI: |
10.3233/npm-2010-0123 |
| Popis: |
Hemolytic anemia with abundant Heinz bodies developed in an extremely low birth weight infant. The infant was born at 25 weeks' gestation with a birth weight of 741 g. The disord er manifested at 28 days of age after the acute period. Results of a routine weekly blood examination showed an unexpected sudden fall in the hemoglobin level and an increased total bilir ubin level. Peripheral blood smear revealed that a high percentage of erythrocytes contained Heinz bodies. With repeated blood transfusions and aggressive phototherapy this condition resolved within a week. The patient had not been exposed to known toxins with oxidizing agents. Glucose-6-phosphate dehydrogenase levels were normal, and an unstable hemoglobin was not present. Although the cause and underlying mechanisms of this phenomenon are unknown, the immature antioxidant function of the erythrocyte membrane against oxygen radicals in an extremely premature infant might be a factor in the etiology. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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