Enantioselective Electrodialysis of Amino Acids with Charged Polar Side Chains through Molecularly Imprinted Polymeric Membranes Containing DIDE Derivatives

Autor:	Masakazu Yoshikawa, Jun-ichiro Izumi, Toshio Kitao
Rok vydání:	1997
Předmět:	Membrane Polymers and Plastics Tetrapeptide Chemistry Selective adsorption Materials Chemistry Side chain Molecularly imprinted polymer Organic chemistry Semipermeable membrane Electrodialysis Molecular imprinting Combinatorial chemistry
Zdroj:	Polymer Journal. 29:205-210
ISSN:	1349-0540 0032-3896
DOI:	10.1295/polymj.29.205
Popis:	Molecularly imprinted polymeric membranes, bearing tetrapeptide derivative H-Asp(OcHex)–Ile-Asp(OcHex)-Glu(OBzl)-CH2-, were prepared during the membrane preparation (casting) process in the presence of print molecule Boc-L-Trp. The molecularly imprinted membranes thus obtained showed adsorption selectivity toward print molecule family, such as L-Arg, L-Lys, L-His, L-Asp, and L-Glu. The tetrapeptide derivative in the molecularly imprinted membranes preferentially recognized L-amino acid from racemic amino acids. Enantioselective electrodialysis was attained with the present membrane, and L-isomer was permeated in preference to D-isomer, while D-isomer was preferentially permeated by using concentration difference as a driving force for membrane transport. It was made clear that the optical resolution was attained by the molecularly imprinted polymeric membranes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::04c26ada4c588ebf8f56b0131a14e15e https://doi.org/10.1295/polymj.29.205 Zobrazit plný text záznamu