Predictive factors for successful sacral nerve stimulation in the treatment of faecal incontinence: results of trial stimulation in 200 patients

Autor: Igor Sielezneff, Jean-Luc Faucheron, Eric Rullier, P. Orsoni, H. Damon, François Mion, Guillaume Meurette, Paul-Antoine Lehur, M. Ouaissi, Francis Michot, Laurent Siproudhis, Club Nemo, J. F. Menard, Muriel Mathonnet, Anne-Marie Leroi, Xavier Barth, S. Gallas, Véronique Desfourneaux, F. Zerbib
Rok vydání: 2010
Předmět:
Zdroj: Colorectal Disease. 13:689-696
ISSN: 1462-8910
DOI: 10.1111/j.1463-1318.2010.02260.x
Popis: Aim Sacral nerve stimulation (SNS) has a place in the treatment algorithm for faecal incontinence (FI). However, after implantation, 15–30% of patients with FI fail to respond for unknown reasons. We investigated the effect of SNS on continence and quality of life (QOL) and tried to identify specific predictive factors of the success of permanent SNS in the treatment of FI. Method Two hundred consecutive patients (six men; median age = 60; range 16–81) underwent permanent implantation for FI. The severity of FI was evaluated by the Cleveland Clinic Score. Quality of life was evaluated by the French version of the American Society of Colon and Rectal Surgeons (ASCRS) quality of life questionnaire (FIQL). All patients underwent a preoperative evaluation. After permanent implantation, severity and QOL scores were reevaluated after six and 12 months and then once a year. Results The severity scores were significantly reduced during SNS (P = 0.001). QOL improved in all domains. At the 6-month follow-up, the clinical outcome of the permanent implant was not affected by age, gender, duration of symptoms, QOL, main causes of FI, anorectal manometry or endoanal ultrasound results. Only loose stool consistency (P = 0.01), persistent FI even though diarrhoea was controlled by medical treatment (P = 0.004), and low stimulation intensity (P = 0.02) were associated with improved short-term outcomes. Multivariate analysis confirmed that loose stool consistency and low stimulation intensity were related to a favourable outcome. Conclusion Stool consistency and low stimulation intensity have been identified as predictive factors for the short-term outcome of SNS.
Databáze: OpenAIRE
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