Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome
| Autor: | Trevor Morgan, Kazuyoshi Aso, Huilin Li, Wenhu Zhan, Gang Lin, Tierra Ouellette, Peter T. Meinke, Carl Nathan, Manoj K. Ramjee, Adrian G. Wright, Hao-Chi Hsu, Toshihiro Imaeda, Mayako Michino, Kenjiro Sato, Kristin Burns-Huang, Ryoma Hara, Michael Foley, Rei Okamoto |
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| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
biology Chemistry biology.organism_classification 01 natural sciences 0104 chemical sciences Microbiology Mycobacterium tuberculosis 010404 medicinal & biomolecular chemistry 03 medical and health sciences Proteasome Drug Discovery Molecular Medicine 030304 developmental biology |
| Zdroj: | Journal of Medicinal Chemistry. 62:9246-9253 |
| ISSN: | 1520-4804 0022-2623 |
| Popis: | Proteasomes of pathogenic microbes have become attractive targets for anti-infectives. Coevolving with its human host, Mycobacterium tuberculosis (Mtb) has developed mechanisms to resist host-impos... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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