Fanconi Syndrome Associated with Hyponatremia in Two Patients with Legionella Pneumonia
| Autor: | Hirotoshi Yasui, Akihiro Ryuge, Taishi Yamakawa, Nobukazu Suganuma, Kenshi Watanabe, Yasuhiko Ito, Rie Nomura, Shuko Mashimo, Shoichi Maruyama, Hitoshi Tanaka |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
030232 urology & nephrology Legionella Pneumonia Legionella pneumophila Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine medicine 030212 general & internal medicine biology business.industry nutritional and metabolic diseases Fanconi syndrome General Medicine medicine.disease biology.organism_classification Hypokalemia respiratory tract diseases Pneumonia medicine.symptom Hyponatremia business Hypophosphatemia Electrolyte Disorder |
| Zdroj: | Internal Medicine. 55:3479-3484 |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | Legionella pneumophila is a cause of community-acquired pneumonia that is reported to induce electrolyte disorders, including hyponatremia, hypokalemia, and hypophosphatemia. We herein report two Japanese men with Legionella pneumonia and hyponatremia and hypophosphatemia. These findings were associated with an elevation of urinary low-molecular-weight tubular protein, including urinary β2-microglobulin, N-acetyl-β-D-glucosaminidase, the fractional excretion of phosphate and uric acid, and the presence of glycosuria and panaminoaciduria, suggesting that their electrolyte disorders had been caused by Fanconi syndrome. In these two cases, hyponatremia was probably due to salt wasting. Electrolyte disorders caused by Legionella pneumonia are corrected by treatment of the primary disease and fluid administration. |
| Databáze: | OpenAIRE |
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