Basic Aspects of Oxidative Stress in Male Reproductive Health

Autor:	Chak-Lam Cho, Ralf Henkel, Michael C. Solomon
Rok vydání:	2019
Předmět:	chemistry.chemical_classification Reactive oxygen species Antioxidant medicine.medical_treatment Sperm dna Biology medicine.disease_cause medicine.disease Sperm Male infertility Andrology chemistry Male fertility medicine Oxidative stress Polyunsaturated fatty acid
DOI:	10.1016/b978-0-12-812501-4.00004-3
Popis:	Spermatozoa are particularly susceptible to oxidative stress (OS) given the high content of polyunsaturated fatty acids contained within their plasma membrane. OS occurs as a result of an imbalance between reactive oxygen species and antioxidants in the body, and is considered a major cause of male infertility. OS negatively impairs sperm function via multiple pathways including induction of sperm DNA damage. Antioxidant supplementation represents one of the possible options in alleviating the detrimental impact of OS on male fertility by restoring or maintaining the delicate redox balance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::04b0d1365c29c3f3e68ecbc1e6201f93 https://doi.org/10.1016/b978-0-12-812501-4.00004-3 Zobrazit plný text záznamu