The role of adenosine receptors in regulating production of tumour necrosis factor-α and chemokines by human lung macrophages

Autor:	F Besnard, S Grassin Delyle, Emmanuel Naline, A Buenestado, Alain Chapelier, JF Bellamy, I Arnould, Philippe Devillier, Sabine Blouquit-Laye
Rok vydání:	2010
Předmět:	Pharmacology medicine.medical_specialty Chemokine medicine.medical_treatment Biology Purinergic signalling Adenosine A3 receptor Adenosine receptor Adenosine Endocrinology Cytokine Internal medicine medicine Cancer research biology.protein Tumor necrosis factor alpha Receptor medicine.drug
Zdroj:	British Journal of Pharmacology. 159:1304-1311
ISSN:	0007-1188
Popis:	Background and purpose: Adenosine is a major endogenous regulator of macrophage function, and activates four specific adenosine receptors (A1, A2A, A2B and A3). Here, we have assessed in human lung macrophages the modulation of the expression of adenosine receptor mRNA by lipopolysaccharide (LPS), and the relative contributions of the different adenosine receptors to LPS-induced production of tumour necrosis factor (TNF)-α and chemokines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::04a5c86c0708dbcc32cc586e65be249f https://doi.org/10.1111/j.1476-5381.2009.00614.x Zobrazit plný text záznamu Plný text ve formátu PDF