Preparation of a radiobrominated fluorescein for liver scanning
| Autor: | Robert L. Dressler, Allan H. Gobuty, Jay A. Spicer |
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| Rok vydání: | 1980 |
| Předmět: |
Chromatography
Organic Chemistry Halogenation Resorcinol Mass spectrometry Biochemistry Thin-layer chromatography Analytical Chemistry chemistry.chemical_compound Column chromatography chemistry Yield (chemistry) Drug Discovery Radiology Nuclear Medicine and imaging Liver scanning Fluorescein Spectroscopy |
| Zdroj: | Journal of Labelled Compounds and Radiopharmaceuticals. 17:73-80 |
| ISSN: | 0362-4803 |
| DOI: | 10.1002/jlcr.2580170108 |
| Popis: | A radiobrominated compound, 4,5,6,7-tetrachloro-2′,4′,5′,7′-tetrabromofluorescein-77Br4 was prepared from resorcinol, tetrachlorophthallic anhydride and Na77Br by a two-step synthesis. The precursor was identified by spectrometry. Final purification utilized column chromatography. The product was identified by thin layer chromatography and spectrometry. The yield was 60% of theoretical. |
| Databáze: | OpenAIRE |
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