ChemInform Abstract: Studies on the Enantioselective Synthesis of α-Amino Acids via Asymmetric Phase-Transfer Catalysis

Autor: P. G. Wainwright, T. R. Lowdon, John Crosby, Barry Lygo, J. A. Peterson
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 32
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.200129176
Popis: In this paper, we describe investigations into the use of cinchona alkaloid-derived quaternary ammonium phase-transfer catalysts for the asymmetric alkylation of a benzophenone-derived glycine-imine. Utility of this process is demonstrated by the enantioselective synthesis of a range of α-amino acid esters.
Databáze: OpenAIRE