Structure and Synthesis of Phenaglydon, a new Quinolone Derived Phenanthridine Alkaloid fromGlycosmis cyanocarpa

Autor: Harald Greger, Gerald Wurz, Otmar Hofer
Rok vydání: 1993
Předmět:
Zdroj: Natural Product Letters. 3:177-182
ISSN: 1057-5634
DOI: 10.1080/10575639308043859
Popis: A novel quinolone derived alkaloid of the phenanthridine type, phenaglydon (2), has been isolated from the lipophilic leaf extract of Glycosmis cyanocarpa (Rutaceae) together with schinifoline (1), a prenylated 2-quinolinone characterized by a diene grouping in the side chain. Both structures have been elucidated on spectroscopic evidence. In the case of phenaglydon the proposed structure has additionally been confirmed by synthesis. The co-occurrence of these alkaloids suggests close biogenetic connections between the two compounds.
Databáze: OpenAIRE