Popis: |
A novel quinolone derived alkaloid of the phenanthridine type, phenaglydon (2), has been isolated from the lipophilic leaf extract of Glycosmis cyanocarpa (Rutaceae) together with schinifoline (1), a prenylated 2-quinolinone characterized by a diene grouping in the side chain. Both structures have been elucidated on spectroscopic evidence. In the case of phenaglydon the proposed structure has additionally been confirmed by synthesis. The co-occurrence of these alkaloids suggests close biogenetic connections between the two compounds. |