ChemInform Abstract: Synthesis of γ-Haloesters and γ-Ketoesters by Homolytic Addition of Carbon Radicals Generated by α-Haloesters and Triethylborane to Alkenes and Silyl Enol Ethers

Autor:	Enrico Baciocchi, E. Muraglia
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Addition reaction chemistry Silylation Radical Triethylborane Electrophile chemistry.chemical_element General Medicine Carbon Enol Medicinal chemistry Homolysis
Zdroj:	ChemInform. 25
ISSN:	0931-7597
Popis:	An efficient synthesis of γ-haloesters has been achieved, under very mild conditions, by addition of electrophilic carbon radicals ·CH(R)CO2Et (R=H, Me, CO2Et) generated by XCH(R)CO2Et (X=Br, I) / BEt3 / air in DMSO to alkenes and cycloalkenes. The synthesis of γ-ketoesters is also possible when silyl enol ethers are used as the substrates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::04808a51b9354dbc0b7a4cdf37db05b3 https://doi.org/10.1002/chin.199434107 Zobrazit plný text záznamu Plný text