Synthesis of fused azacycle via Overman rearrangement and ring-rearrangement metathesis as key steps
Autor: | Sambasivarao Kotha, Ongolu Ravikumar |
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Rok vydání: | 2016 |
Předmět: |
010405 organic chemistry
Stereochemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry Metathesis Ring (chemistry) 01 natural sciences Biochemistry 0104 chemical sciences Stereocenter Ruthenium Overman rearrangement chemistry.chemical_compound chemistry Nitrogen atom Dicyclopentadiene Drug Discovery |
Zdroj: | Tetrahedron Letters. 57:1994-1996 |
ISSN: | 0040-4039 |
DOI: | 10.1016/j.tetlet.2016.03.087 |
Popis: | A simple and concise approach to fused tricyclic compound containing five stereogenic centers and one nitrogen atom is described starting with a readily available building block dicyclopentadiene. This route involves the Overman rearrangement and ruthenium catalyzed ring-rearrangement metathesis as key steps. |
Databáze: | OpenAIRE |
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