In Vivo Acquired Resistance to Fluorquinolones in Helicobacter pylori During Therapy with Ciprofloxacin Alone or Ciprofloxacin plus Amoxicillin Clavulanate

Autor: Boixeda D, F. Baquero, M. T. Serrano, M. Garcia-Gonzalez, L. De Rafael, Rafael Cantón
Rok vydání: 1993
Předmět:
Zdroj: Helicobacter pylori and Gastroduodenal Pathology ISBN: 9783642774881
Popis: In vitro Helicobacter pylori is susceptible to several antimicrobial agents [1–3]. However, the long-term eradication of this organism from the gastric mucosa after a 3- or 4-week therapy seems rather difficult. In most cases a single-drug therapy is remarkably ineffective, and even the association of two or three substances achieves only the clearance or temporal eradication of H. pylori from the colonised gastric mucosa in humans. Relapse following what appears to be a successful treatment is common and probably due to incomplete eradication of this organism [4]. The conventional therapy includes not only the antimicrobial agents, but also gastric inhibiting substances [5].
Databáze: OpenAIRE