Early and Mid-Term Outcomes of Transcatheter Aortic Valve Replacement Using the New Generation Self-Expanding Corevalve Evolut R Device

Autor: Antonino Indelicato, Daniela Giannazzo, Marco Barbanti, Maria Cristina Portelli, Ketty La Spina, Davide Capodanno, Sebastiano Immè, Gerlando Pilato, Paolo D'Arrigo, Simona Gulino, Wanda Deste, Martina Patanè, Piera Capranzano, Giuliano Costa, Andrea Picci, Denise Todaro, Corrado Tamburino, Emanuela Di Simone, Carmelo Sgroi, Claudia Tamburino
Rok vydání: 2018
Předmět:
Zdroj: Structural Heart. 2:229-234
ISSN: 2474-8706
DOI: 10.1080/24748706.2018.1440097
Popis: Background: To assess early and mid-term efficacy of transcatheter aortic valve replacement (TAVR) using the new-generation CoreValve Evolut R (Medtronic Inc., Galway, Ireland).Methods: This is a prospective, single-center study. All consecutive patients undergoing TAVR with 23-, 26-, 29-, 34-mm Evolut R valve were included. In a secondary analysis, patients undergoing Evolut R implantation were compared using the propensity score method with a historical cohort of patients who underwent CoreValve implantation in our institution.Results: From March 2015 to September 2017, a total of 320 patients with a median age of 81.1 years (IQR 77–84) and mean STS score of 4.9 ± 3.1% were treated. Device success was obtained in 300 patients (93.8%). Effective recapture and repositioning of the valve due to initial suboptimal deployment was accomplished in 40 patients (12.5%). Post-TAVR transthoracic echocardiogram showed a reduction in mean gradient from 49.1 ± 18.2 mmHg to 7.6 ± 0.4 mmHg (p
Databáze: OpenAIRE