Autor:	Margarita Alfimova, Kaleda Vg, Shcherbatykh Tv, Lilia I. Abramova, Vera Golimbet, Evgeny I. Rogaev
Rok vydání:	2001
Předmět:	Genetics Psychosis biology business.industry media_common.quotation_subject Biophysics medicine.disease Neuroticism Structural Biology Polymorphism (computer science) mental disorders Genotype medicine biology.protein Temperament Allele Big Five personality traits business Serotonin transporter Clinical psychology media_common
Zdroj:	Molecular Biology. 35:336-338
ISSN:	0026-8933
DOI:	10.1023/a:1010410409091
Popis:	Some studies associate the insertion/deletion polymorphism of the serotonin transporter (5-HTT) gene with anxiety-related personality traits in mentally healthy people, the short (s) allele being associated with a higher neuroticism score. The 5-HTT genotype and neuroticism score were established for 114 affective patients, 87 healthy relatives of endogenous psychosis patients, and for 156 mentally healthy people without familial psychiatric history. The effects of sex and age on the association between the two parameters was studied. Neuroticism proved to be not associated with the 5-HTT genotype.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::040fe696707d14aee5f9fe148acc10ee https://doi.org/10.1023/a:1010410409091 Zobrazit plný text záznamu Full text from SpringerLink