ANTIMICROBIAL EFFECT OF IODOFORM AND CHLORHEXIDINE ON MUSEUM STRAINS OF MICROORGANISMS
| Autor: | M. M. Ananieva, M. O. Faustova, V. M. Havryliev, Yu.V. Chumak, G. A. Loban |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
biology
business.industry medicine.drug_class Chlorhexidine biology.organism_classification Antimicrobial medicine.disease_cause Iodoform Enterococcus faecalis Microbiology chemistry.chemical_compound Antiseptic chemistry Staphylococcus epidermidis Staphylococcus aureus Medicine business Candida albicans medicine.drug |
| Zdroj: | Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії. 21:93-97 |
| ISSN: | 2077-1126 2077-1096 |
| DOI: | 10.31718/2077-1096.21.1.93 |
| Popis: | Surgical tooth extraction can result in a number of complications. Alveolitis is an infectious and inflammatory process in the walls of a tooth socket that may occur after tooth extraction during at the oral surgery outpatient appointment. This condition is characterized by a partial or complete absence of a blood clot, called as "dry socket", and pain syndrome. There are various factors, which can contribute to the development of this process, but the most common are traumatic and infectious ones. For the local treatment of alveolitis, a number of drugs are used to eliminate inflammatory manifestations and pain syndrome. During an outpatient appointment for the treatment of alveolitis, antiseptic drugs as iodoform and chlorhexidine are most often used. Iodoform is an antiseptic widely used locally in oral surgery and in endodontics. Chlorhexidine is also widely used in dentistry as an antiseptic. The aim of this in vitro study is to investigate the antimicrobial properties of iodoform and chlorhexidine using museum strains of microorganisms. Materials and methods. Museum strains of Staphylococcus aureus ATCC 25923, Staphylococcus epidermidis ATCC 14990, Enterococcus faecalis ATCC 29212, Esherichia coli ATCC 25922, Candida albicans ATCC 10231 were used the studied cultures of microorganisms. The antimicrobial effect of iodoform and chlorhexidine was determined by a quantitative method of serial dilutions in broth and agar. For this purpose, we used iodoform suspension, which corresponded to 200.0 mg / ml of the working concentration of the agent. A 0.05% solution of chlorhexidine bigluconate was used that corresponded to 500 μg / ml of the working concentration of the agent. Results and discussion. Iodoform as powder in the studied concentrations caused an insignificant static effect on museum strains of E. faecalis, E. coli, but did not exhibit a bactericidal effect against them. In relation to the C. albicans strain, iodoform demonstrated fungiostatic properties. The S. epidermidis and S. aureus strains were resistant to iodoform. Chlorhexidine caused both inhibitory and microbicidal action on all studied strains of microorganisms. |
| Databáze: | OpenAIRE |
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