A Systematic Review of One Anastomosis/Mini Gastric Bypass as a Metabolic Operation for Patients with Body Mass Index ≤ 35 kg/m2

Autor: Chetan Parmar, Kamal Mahawar, Roxanna Zakeri
Rok vydání: 2019
Předmět:
Zdroj: Obesity Surgery. 30:725-735
ISSN: 1708-0428
0960-8923
Popis: One anastomosis/mini gastric bypass (OAGB-MGB) is now an established bariatric procedure for patients suffering from obesity. The purpose of this review is to evaluate the role of this operation in patients with body mass index (BMI) ≤ 35 kg/m2. A literature review was performed as per preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. This review reports cumulative results of 376 OAGB-MGB procedures with a mean age of 44.28 years and mean BMI of 29.16 kg/m2 (range 22–35). Females represented 67.67% of the patients. The leak rate was 0.27%. The mean follow-up was 32.6 months (6–84 months). The mean operative time was 89.45 min. The median limb length was 120 cm (range 100–200 cm). The mean fasting plasma glucose (FPG) decreased from 196.97 to 103.28 mg/dL. The mean HbA1c came down from 9.13% preoperatively to 6.14% postoperatively. The total cholesterol levels came down from a mean of 197.8 mg/dL preoperatively to 120.6 mg/dL postoperatively. The low-density lipoprotein (LDL) and triglyceride levels came down from 127.7 and 209.3 mg/dL to 81 and 94.8 mg/dL, respectively. Mortality was 0%. Marginal ulceration rate of 6.3% and an anaemia rate of 4.7% were reported. Low albumin was reported in 1 (0.2%) patient. The mean BMI came down to 23.76 kg/m2 at 12 months. We conclude that there is now satisfactory evidence to consider OAGB-MGB as a safe and effective metabolic procedure for diabetic patients with BMI ≤ 35 kg/m2. Randomised studies comparing different bariatric procedures with longer term follow-up are needed.
Databáze: OpenAIRE
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