Efficient Buchwald–Hartwig and nitrene-mediated five-membered ring closure approaches to the total synthesis of quindoline. Unexpected direct conversion of a nitro group into a phosphazene
| Autor: | Elida N. Thobokholt, Sebastián O. Simonetti, Teodoro S. Kaufman, Enrique L. Larghi, Andrea B. J. Bracca |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | RSC Advances. 13:13715-13724 |
| ISSN: | 2046-2069 |
| Popis: | Two total syntheses of quindoline were achieved. The PPh3-mediated generation of a key nitrene caused the unprecedented formation of a phosphazene. The reaction mechanism was studied by a DFT approach. |
| Databáze: | OpenAIRE |
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