Effect of meso substituents on the NH acidities of benzimidazoles

Autor:	T. V. Kashik, S. M. Ponomareva, G. G. Skvortsova, Abramova Nina D
Rok vydání:	1983
Předmět:	chemistry.chemical_compound chemistry Intramolecular force Organic Chemistry Inorganic chemistry Potentiometric titration Substituent Acetonitrile Medicinal chemistry
Zdroj:	Chemistry of Heterocyclic Compounds. 19:997-1000
ISSN:	1573-8353 0009-3122
DOI:	10.1007/bf00506888
Popis:	The NH acidities of a systematic series of 2-substituted benzimidazoles in acetonitrile were studied by potentiometric titration. It was found that the intramolecular interrelationships between the substituent in the 2 position and the acidity center have primarily inductive character and are expressed quantitatively by a dependence of the pKa = f(σm) type.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::03ff84caca81683a4d7185e005814044 https://doi.org/10.1007/bf00506888 Zobrazit plný text záznamu Full text from SpringerLink