Separation of chiral phases in monolayer crystals of racemic amphiphiles

Autor:	J. H. Kim, N. M. Peachey, Craig J. Eckhardt, R. A. Uphaus, X. Gong, James M. Takacs, J. Wang, David Swanson, M. A. Khan
Rok vydání:	1993
Předmět:	Multidisciplinary Stereochemistry Chemistry Atomic force microscopy High Energy Physics::Lattice Resolution (electron density) law.invention Chemical physics law Monolayer Amphiphile Mica Crystallization Enantiomer
Zdroj:	Nature. 362:614-616
ISSN:	1476-4687 0028-0836
DOI:	10.1038/362614a0
Popis:	OPTICAL activity manifested by chiral molecules and crystals is of long-standing interest in physics, chemistry, biology and geology1,2. The structure of chiral lattices in two and three dimensions may provide insights into chiral discrimination, and chiral phases play an important part in the physics and applications of liquid-crystal and amphiphilic films3–7. Here we report the observation of spontaneous separation of chiral phases in an oriented monolayer of rigid, chiral amphiphiles deposited on mica. Atomic force microscopy of the ordered films reveals domains of mirror-image structures. We propose that this may be the signature of separation into domains of pure enantiomers, although other possibilities exist. This separation of chiral phases in two dimensions may be considered analogous to the spontaneous resolution of enantiomers in three-dimensional crystallization, as exploited by Pasteur in 1848 to isolate enantiomers of sodium tartrate1.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::03e0c56e22fd6180a056455048bba80b https://doi.org/10.1038/362614a0 Zobrazit plný text záznamu