Gender influence on the level of expression of oral fluid biomarkers

Autor:	Yu. S. Podolskii, E. O. Kudasova, Liliya V. Gavryushova, E. V. Kochurova, E. V. Izhnina
Rok vydání:	2020
Předmět:	stomatognathic diseases Expression (architecture) business.industry Dental health Dental examination General Engineering Energy Engineering and Power Technology Oral fluid Physiology Medicine General health Matrix metalloproteinase business
Zdroj:	Russian Journal of Dentistry. 24:92-94
ISSN:	2413-2934 1728-2802
Popis:	The purpose to determine the level of expression in the oral fluid of matrix metalloproteinases (MMPs) of types 2, 8 and 9, as well as their tissue inhibitors (TIMPs) of types 1 and 2, depending on the presence or absence of a number of components of the dental status.Material and methods. The results of a study of the level of expression of oral fluid biomarkers of 19 patients with different levels of dental health who do not have a history of history are presented. Previously, a dental examination of patients was carried out and the occurrence of signs of dental status was determined.Results and discussion. Analysis of expression levels of matrix metalloproteinases and their tissue inhibitors showed significant differences in performance.Conclusions. The data obtained suggest a significant impact of the state of dental health mainly on the level of MMP-2 and MMP-9, the indicators of which differ 2 times from the same in the opposite sex, with other conditions being almost the same (age, general health).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::03d621f67fcf285d32195ca0d4af7e2a https://doi.org/10.17816/1728-2802-2020-24-2-92-94 Zobrazit plný text záznamu