Infertility: Hydrosalpinges in in-vitro fertilization: an unfavourable prognostic feature
| Autor: | Jean Vandromme, Annick Delvigne, Bernard Lejeune, Emmanuel Chasse, Michel Van Rysselberge, Fernand Leroy |
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| Rok vydání: | 1995 |
| Předmět: |
Infertility
Gynecology medicine.medical_specialty Pregnancy animal structures In vitro fertilisation business.industry Obstetrics medicine.medical_treatment Rehabilitation Obstetrics and Gynecology medicine.disease Pregnancy rate Human fertilization Reproductive Medicine Salpingectomy medicine Gestation business Hydrosalpinx |
| Zdroj: | Human Reproduction. 10:576-579 |
| ISSN: | 1460-2350 0268-1161 |
| DOI: | 10.1093/oxfordjournals.humrep.a135992 |
| Popis: | The aim of this study was to determine whether the presence of a hydrosalpinx influences in-vitro fertilization (IVF) prognosis. Comparisons were made between 69 IVF cycles in 37 patients carrying hydrosalpinges (hydrosalpinx group) and 67 IVF cycles in 41 patients without tubes or surgically sterilized (control group). Twenty-two patients carrying hydrosalpinges underwent salpingectomy or salpingoplasty (operated group); they then underwent 42 IVF trials which were compared with the two former groups. In the hydrosalpinx group, pregnancy rates by oocyte retrieval were 10.1% for clinical and ongoing pregnancies. In the control group, the corresponding pregnancy rates were 23.0 and 21.3% respectively. The implantation rate per embryo was 4.2% for clinical and ongoing pregnancies in the hydrosalpinx group and 11.0 and 10.4% respectively in the control group. The operated group had pregnancy rates of 38.1% for clinical pregnancies and 31.0% for ongoing pregnancies, with implantation rates of 17.4 (clinical) and 14.8% (ongoing) respectively. Pregnancy and implantation rates were statistically lower in the hydrosalpinx group as compared with controls and with the operated group. The differences between control and operated groups were not significant. In conclusion, the presence of a hydrosalpinx is thus associated with poor prognosis in IVF treatment. Surgical correction of such lesions appears to restore high success rates. |
| Databáze: | OpenAIRE |
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