Effect of the Maize-Derived Compounds DIMBOA and MBOA on Growth and Digestive Processes of European Corn Borer (Lepidoptera: Pyralidae)

Autor:	N. M. R. Thie, Jeffrey Atkinson, Bernard J. R. Philogène, Francisca Campos, Peter Morand, John T. Arnason, Jon G. Houseman
Rok vydání:	1992
Předmět:	European corn borer Chymotrypsin Protease Ecology biology medicine.medical_treatment General Medicine biology.organism_classification Trypsin Ostrinia DIMBOA chemistry.chemical_compound chemistry Insect Science Botany biology.protein medicine Food science Digestion Pyralidae medicine.drug
Zdroj:	Journal of Economic Entomology. 85:669-674
ISSN:	1938-291X 0022-0493
DOI:	10.1093/jee/85.3.669
Popis:	The maize derived growth inhibitor, 2,4-dihydroxy-7-methoxy-l,4-benzoxazin-3-one (DIMBOA), and one of its degradation products, 6-methoxybenzoxazolin-3-one (MBOA), were assessed for their mode of action on larvae of the European corn borer, Ostrinia nubilalis (Hubner). Nutritional indices computed for larvae administered the compounds in their diets showed that DIMBOA reduced the approximate digestibility of food and that MBOA reduced the efficiency of conversion of digested food. The results suggested that DIMBOA acts primarily as a digestive toxin and that the effects of MBOA occurred after digestion. Based on measurements of hydrolysis of artificial protease substrates, inclusion of DIMBOA or MBOA in diet ingested for 48 h or with crude gut homogenates reduced the activity of trypsin. Inclusion of DIMBOA decreased the activity of chymotrypsin on artificial substrates. DIMBOA inhibition of partially purified larval corn borer chymotrypsin was noncompetitive.
Databáze:	OpenAIRE
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