Prevention of Ethanol-induced Gastric Mucosal Microcirculatory Disturbances by Mild Irritant Through the Actions of Calcitonin Gene-Related Peptide and Prostaglandin I2 in Rats

Autor:	Sumito Mizuguchi, Takashi Ohno, Kazuhisa Kamata, Katsuharu Arai, Masataka Majima, Katsunori Saigenji, Kouichiro Hattori, Takeo Saeki
Rok vydání:	2006
Předmět:	business.industry Prostaglandin Blood flow Calcitonin gene-related peptide Pharmacology Pathophysiology Microcirculation chemistry.chemical_compound Basal (phylogenetics) medicine.anatomical_structure chemistry Gastric mucosa medicine business Intravital microscopy
Zdroj:	Organ Microcirculation ISBN: 4431221352
DOI:	10.1007/4-431-27174-0_12
Popis:	Disturbances in the gastric mucosal microcirculation are thought to be an important cause of injury, and observation of the microcirculation is therefore important for revealing the pathophysiology of that injury. In the present study, we investigated the mechanism of adaptive cytoprotection of 1 M NaCl against ethanol [1] by observing the microcirculation in the basal part of the gastric mucosa of rats using intravital microscopy [2–4] to clarify the mediators involved in the maintenance of the integrity of the mucosal blood flow.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::036768fe688aeb2e7b83b8cfb777aaa6 https://doi.org/10.1007/4-431-27174-0_12 Zobrazit plný text záznamu