477 Efficient ex-vivo COL7A1 correction of patient's primary keratinocytes and fibroblasts using RNP-based CRISPR/Cas9 and homology-directed repair to treat recessive dystrophic epidermolysis bullosa
Autor: | A. Izmiryan, C. Berthault, O. Gouin, M. Chen, D. Woodley, S. Gaucher, A. Hovnanian |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Journal of Investigative Dermatology. 142:S81 |
ISSN: | 0022-202X |
DOI: | 10.1016/j.jid.2022.05.486 |
Databáze: | OpenAIRE |
Externí odkaz: |