477 Efficient ex-vivo COL7A1 correction of patient's primary keratinocytes and fibroblasts using RNP-based CRISPR/Cas9 and homology-directed repair to treat recessive dystrophic epidermolysis bullosa

Autor: A. Izmiryan, C. Berthault, O. Gouin, M. Chen, D. Woodley, S. Gaucher, A. Hovnanian
Rok vydání: 2022
Předmět:
Zdroj: Journal of Investigative Dermatology. 142:S81
ISSN: 0022-202X
DOI: 10.1016/j.jid.2022.05.486
Databáze: OpenAIRE