Childhood Bullous Pemphigoid: A Case Report and Literature Review
| Autor: | Ding-Dar Lee, Chien-Lun Hsu, Keh-Gong Wu, Chun-Jen Chen, Ming-Luen Lee, Chia-Sui Chou |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Immunoglobulin A
Epidermolysis bullosa acquisita medicine.medical_specialty Pathology integumentary system medicine.diagnostic_test biology business.industry medicine.disease Childhood bullous pemphigoid Dermatology eye diseases immune system diseases Skin biopsy medicine biology.protein sense organs Bullous pemphigoid Differential diagnosis skin and connective tissue diseases business Direct fluorescent antibody Subepidermal blisters |
| Zdroj: | Journal of Clinical & Experimental Dermatology Research. 4 |
| ISSN: | 2155-9554 |
| DOI: | 10.4172/2155-9554.s6-010 |
| Popis: | Bullous pemphigoid is a very rare dermatologic disorder in children. We report a 1-year and 9-month-old boy, who was diagnosed childhood bullous pemphigoid on the basis of clinical findings and confirmed by skin biopsy showing subepidermal blisters with dermal layer infiltrated with neutrophils, a unique histological finding. The result mimicked the histological findings of linear immunoglobulin A bullous disease. Direct immunofluorescence showed linear deposits of IgG and C3 at dermal-epidermal junction, similar to epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. We suggested the differential diagnosis of subepidermal blisters should include linear immunoglobulin A bullous disease of childhood, epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|