| Autor: |
Grzegorz Buszewicz, Roman Mądro, Paweł Szpot, Krzysztof Bańka |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Current Issues of Pharmacy and Medical Sciences. 25:401-403 |
| ISSN: |
2084-980X |
| DOI: |
10.12923/j.2084-980x/25.4/a.13 |
| Popis: |
The report presents a method for determining imazalil and thiabendazole in a liquid grapefruit extract-containing dietary supplement using the ultra performance liquid chromatography coupled to quadrupole-time-of-flight tandem mass spectrometry (UPLC-Q-TOF-MS) system. The employment of hybrid quadrupole coupled with time-of-flight analyzer characterized by a very high resolution allows for identifying the investigated compounds and for employing the developed technique in routine quality control of natural extracts-containing foodstuffs. The limit of detection for imazalil was 0.25 ng/ml, while for thiabendazole its value was 2 ng/ml. The recovery of the investigated fungicides was within the range of 84-109 %. In the studied dietary supplement, the investigators demonstrated trace amounts of imazalil and thiabendazole, what may be explained by biocide diffusion into the flesh of fruits employed in manufacturing products of this type. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
