Cu(OAc)2-Catalysed Oxidative Dual C-H/N-H Activation of Terminal Alkynes andN-Deprotected Sulfonimidamides: An Easy Access toN-Alkynylated Sulfonimidamides

Autor:	Sudhakar R. Kota, Hendrick G. Kruger, Thavendran Govender, Per I. Arvidsson, Tricia Naicker, Ganesh Chandra Nandi
Rok vydání:	2015
Předmět:	Hydrolysis Chemistry Organic Chemistry Organic chemistry Oxidative phosphorylation Physical and Theoretical Chemistry Medicinal chemistry
Zdroj:	European Journal of Organic Chemistry. 2015:2861-2867
ISSN:	1434-193X
Popis:	We report a mild and efficient Cu(OAc)2-catalysed protocol for the oxidative C–N cross-coupling of terminal alkynes and N-deprotected sulfonimidamides. The reaction leads to hitherto unknown N-alkynylated sulfonimidamides. Furthermore, we found that the synthesised N-alkynylated sulfonimidamides could undergo silica-gel-mediated hydrolysis to give the corresponding N-acyl-sulfonimidamides, as well as borane–dimethyl sulfide-mediated reduction to give the corresponding N-alkylated sulfonimidamides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::03587e969a2f14763892b22303eb155c https://doi.org/10.1002/ejoc.201500239 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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