A technique for functional liver autotransplantation

Autor: S.K. Tamvakopoulos, H.T. Randall, J.L. Van Lancker
Rok vydání: 1969
Předmět:
Zdroj: Journal of Surgical Research. 9:449-453
ISSN: 0022-4804
DOI: 10.1016/0022-4804(69)90117-6
Popis: A two-stage technique for successful liver autotransplantation in the rat is described. In the first stage a portion of liver is attached to the spleen for the purpose of establishing adequate collateral circulation. Bile drainage is secured by catheterizing the bile duct of the autotransplant with a polyethylene tube. In the second stage, a portion of liver attached to the spleen is separated from the bulk of the liver and a Roux-en-Y hepatojejunostomy is performed. No difference in the histological appearance, the glucose-6-phosphatase activity, DNA, and protein contents between transplant and liver in situ could be demonstrated. After partial hepatectomy of the liver in situ incorporation of tritium-labeled thymidine was the same in the remnant in situ and in the autotransplant.
Databáze: OpenAIRE