Thiourea linked glycolipid-assisted synthesis of sub-micrometer sized polyaniline spheres for enzyme less sensing of dopamine
| Autor: | M. Mathiselvam, Ramya Ramkumar, M.V. Sangaranarayanan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Materials science
General Chemical Engineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Electrochemistry Ascorbic acid 01 natural sciences Amperometry 0104 chemical sciences Dielectric spectroscopy chemistry.chemical_compound Chemical engineering Thiourea chemistry Polymerization Nafion Polyaniline Materials Chemistry 0210 nano-technology |
| Zdroj: | Journal of Applied Electrochemistry. 50:439-449 |
| ISSN: | 1572-8838 0021-891X |
| Popis: | A simple methodology of synthesizing sub-micrometer sized polyaniline (PANI) spheres using gold electrodes with thiourea linked glycolipid self-assembly for the selective detection of dopamine (DA) is reported here. The synthesis was carried out using a potentiodynamic polymerization method. The self-assembled thiourea linked glycolipid on the gold electrodes and the same lipid acting as the surface directing agent for the formation of polyaniline microspheres is the highlighting factor in this work. The biocompatible sub-micrometer polyaniline spheres are characterized using scanning electron microscopy and transmission electron microscopy studies. Amperometry and electrochemical impedance spectroscopy were employed to estimate the concentration of dopamine. The amperometric studies reveal a linear range of ~ 1 to 640 μM, sensitivity of 370 μA cm−2 μM−1, a very low detection limit of 10 nM, and a response time of ~ 5 s. The interference from l-Dopa, ascorbic acid and uric acid has been minimized on account of the Nafion (Nf) coating and selectivity of the electrode. Real sample analysis was carried out using standard addition method. Schematic representation for the formation of sub-micrometer PANI spheres using thiourea linked glycolipid on Au electrodes for sensing of dopamine. |
| Databáze: | OpenAIRE |
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