Ultrasonographic assessment of dengue fever and its correlation with platelet count
| Autor: | Kamrun Nahar, Mahmood-uz- Jahan, Shamima Akhter, Saikat Barua, Dilara Begum, Mohammed Kamrul Hasan |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Bangladesh Medical Research Council Bulletin. 47:23-28 |
| ISSN: | 2224-7238 0377-9238 |
| DOI: | 10.3329/bmrcb.v47i1.55794 |
| Popis: | Background: Dengue virus infections are a significant threat to human populations particularly in the tropical and subtropical regions. This is mainly transmitted by Aedes aegypti mosquito from humans to humans. The main pathological mechanisms associated include thrombocytopenia, haemorrhagic diathesis with haemoconcentration. Ultrasonography is used because of its ability to detect plasma leakage signs and prediction of disease severity. Objective: To evaluate the usefulness of ultrasonographic findings of dengue fever and its correlation with platelet count. Methods: It was a prospective observational study, carried out in Bangladesh Medical College Hospital, Dhaka from May 2019 to August 2019. A total of 213 patients of suspected dengue fever during the epidemic were included in this study. All the cases were serologically diagnosed and evaluated with ultrasonographic findings. Platelet counts were estimated in all the cases and compared with findings recorded on ultrasonographic findings. Results: The mean age of the study population was 28.7 years. The male female ratio was 1.7:1. The common features on ultrasonography were thickened and oedematous gall bladder wall, mild to moderate ascites, pleural effusion (unilateral and bilateral), and hepatosplenomegaly. Thickened and oedematous gall bladder wall were observed in 68.8%, mild to moderate ascites 65.3%, bilateral pleural effusion 58.2 %, unilateral pleural effusion 40.4%, hepatomegaly 34.3 % and splenomegaly 13.6 % Platelet counts were significantly lower in abnormal ultrasonographic findings (p=0.001). Conclusion: In a febrile patient with thrombocytopenia and positive dengue serology, ultrasonography of the abdomen is a useful tool to evaluate the severity of illness. Ultrasound findings of gall bladder wall oedema, ascites, and pleural effusion were correlated with the severity of thrombocytopenia. In epidemic scenarios, Ultrasonographic features may help in roughly estimating the platelet count even before serology and platelet results are available. Thus, it helps in treatment planning without waiting for the laboratory results. Bangladesh Med Res Counc Bull 2021; 47(1): 23-28 |
| Databáze: | OpenAIRE |
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