Clinical significance of the quantitative assessment of estrogen receptors in advanced breast cancer

Autor:	Richard Sylvester, E. Ferrazzi, Robert Paridaens, Nicole Legros, Jean-Claude Heuson, Guy Leclercq
Rok vydání:	1980
Předmět:	Gynecology Oncology Cancer Research medicine.medical_specialty education.field_of_study business.industry Population Cancer Estrogen receptor medicine.disease Logistic regression Primary tumor Breast cancer Internal medicine medicine Clinical significance business education Tamoxifen medicine.drug
Zdroj:	Cancer. 46:2889-2895
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(19801215)46:12+<2889::aid-cncr2820461430>3.0.co;2-4
Popis:	The predictive value of the (ER) estrogen receptor assay with regard to the response to hormonal treatment was analyzed in women with advanced breast carcinoma. The significance of clinical variables of putative prognostic value was also investigated. A total of 49 courses of endocrine therapy were available for study. The respective merits of using the receptor information as a qualitative or a quantitative variable were compared. Linear logistic regression analysis showed that the quantitative information was significantly related to the therapeutic response (P
Databáze:	OpenAIRE
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