Häufigkeit und Bedeutung von kleinen fokalen Leberläsionen in der MRT

Autor:	D. Pauleit, A. Krämer, H. H. Schild, R. Conrad, R. Bachmann, Burkhard Kreft
Rok vydání:	2001
Předmět:	medicine.medical_specialty Pathology Cirrhosis medicine.diagnostic_test Vascular disease business.industry medicine.disease Malignancy Metastasis Angioma Hepatocellular carcinoma Biopsy medicine Radiology Nuclear Medicine and imaging Radiology Differential diagnosis business
Zdroj:	RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 173:424-429
ISSN:	1438-9010 1438-9029
DOI:	10.1055/s-2001-13340
Popis:	PURPOSE Analysis of the frequency and significance of small focal liver lesions (< or = 2 cm) detected on MRI in the presence or absence of a history of malignancy. METHODS 628 MRI examinations of the liver performed during 1994-1996 were evaluated. The inclusion criterion into the study was the detection of a focal liver lesion with a size < or = 2 cm. The frequency, the size, the diagnostic proof, and the differential diagnosis of the focal liver lesions were analysed with regard to the patients history of a known malignant tumor. RESULTS Overall, 179 of the 628 patients (28.5%) had focal liver lesions < or = 2 cm (n = 338). 58.9% of the lesions could be classified based upon follow-up studies by ultrasound, CT or MRI, or by biopsy. The remaining 41.1% of the lesions could not be classified due to the absence of follow-up examinations. 57.3% of all proven lesions were benign and 42.7% were malignant. A history of a malignant tumor was present in 76.7% of all patients with small liver lesions; however, lesions were benign in these patients in 50.6% of the cases. In patients with no known history of a malignancy, 75% of the lesions were benign and 25% were malignant. However, these malignant lesions were in 10/11 cases hepatocellular carcinomas in patients with liver cirrhosis. CONCLUSION Even in the presence of a history of a malignant tumor, about 50% of the detected small liver lesions on MRI are benign. In the absence of a tumor history the probability of a small malignant liver lesion is very low, if the patients does not have liver cirrhosis where small hepatocellular carcinomas can be present.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::02df1ccd742d7f18e5bae0052b852011 https://doi.org/10.1055/s-2001-13340 Zobrazit plný text záznamu